Back to Tim Ferriss

The Treatment That Took My Anxiety From 8 to 1

Tim FerrissMarch 16, 20268m
In a Nutshell

Accelerated TMS, especially the Stanford-developed SAINT protocol, delivers 3-5 months of conventional depression/OCD/anxiety treatment in 5 intensive days, achieving 70-80% remission rates. Speaker's first 5-day course dropped severe OCD ruminations and 8/10 anxiety to zero for 3-4 months, with even better sustained results (to 1/10) from a recent one-day session enhanced by D-cycloserine for neuroplasticity. Combine with intermittent ketosis and metabolic psychiatry basics like exercise/diet for transformative quality-of-life gains unresponsive to meds.

AI-Generated Notes

These notes were generated by AI and may contain inaccuracies.

Accelerated TMS (transcranial magnetic stimulation) is a type of brain stimulation that has existed for decades, with dramatic improvements in hardware and software over the last 5-10 years, especially the last 5 years, thanks to researchers like Nolan Williams at Stanford, who passed away in the last 6 months.

Conventional TMS involves placing a paddle against the head to produce a magnetic field that excites or inhibits specific brain circuitry. It can treat depression, neurodegenerative diseases, anxiety, OCD, depending on coil placement. Accelerated TMS compresses 3-5 months of conventional TMS into one week: 10 hours a day, every hour on the hour, with 3-9 minutes of pulses followed by 50 minutes off.

The SAINT protocol (developed at Stanford) produces 70-80% remission of depression in many patients, which is durable. Typically a 5-day sequence, followed by 1-3 day boosters at 3 and 6 months.

Speaker has experimented with accelerated TMS over the last few years. First treatment had near-miraculous results: officially diagnosed moderate-severe OCD with ruminative loops (not compulsions like flipping switches, but inescapable thought loops on grudges, fears, planning, conversations), causing insomnia, fatigue, depression. Sequence starts with anxiety. Symptoms at 7-8/10 (severely affecting all life aspects) before 5-day treatment.

Delayed onset: nothing for 2-3 weeks, then switch flipped to zero anxiety and rumination for 3-4 months—better than any psychedelic-assisted therapies. Recommend conversation with Nolan Williams for more details.

Subsequent boosters had null effect, leading to lost hope.

Recent one-day accelerated TMS in Northern California (equivalent to 3 months of conventional TMS), predosed with D-cycloserine (DCS; antiquated antibiotic for tuberculosis and UTIs, affects NMDA receptors as partial antagonist or agonist—catalyst for neuroplasticity). Results better than 7 years ago: switch flipped the next day, now 2-3 months with sustained effects (anxiety from 8/10 to 1/10).

Particularly effective for depression, and in small sample for anxiety and OCD. Combined with basics: exercise, diet, macronutrients.

Intermittent ketosis (achieved via ketogenic diet or other ways) phenomenal for psychiatric and psycho-emotional pains unresponsive to medication. Metabolic psychiatry researched by Chris Palmer at Harvard and others.

A different life.

From 8/10 nonstop ruminative monkey mind fixated on anxiety-producing things to 1-2/10: two entirely different lived experiences, impossible to overstate the difference.

Keep Tim Ferriss in your library

Save the videos and channels worth coming back to, and find them again in one place.