Why Supplements Help Less Than You Think (What To Do Instead)
These notes were generated by AI and may contain inaccuracies.
Randy asks about supplementing with quercetin, which is mentioned frequently. Prefer getting quercetin and other supplements like N-acetylcysteine in natural form because it produces benefits in a more natural state with fewer side effects. Science shows benefits of supplements, but opinion is that natural forms of these beneficial molecules, substances, and metabolites are better than supplements. Challenging to get adequate amounts naturally, so occasionally use supplements personally, but weigh pros and cons. Important not to take them in a fasted state, except things in water.
Ancestors drank water even when not eating or hunting. Water contains calcium, magnesium, potassium, lithium, bacteria, yeast, fungi, and undetectable species of life forms that optimized the microbiome. Living water contributed to microbiome optimization. Modern water is diseased, polluted, with imbalanced life forms, risking pathogenic microbes. In the past, beneficial microbes balanced pathogens. Not advocating drinking creek, river, or lake water unless pristine like Lake of the Woods in Canada, suitable for consumption even near diseased people with poor diets camping nearby. Some alphas could drink closer to shore.
Water is an interesting paradigm for fasted state intake: yes to microbes for optimization, no to calories; yes to minerals and electrolytes, no to amino acids, quercetin, fisetin, cyanidin.
Consume vegetable fermented brine from kimchi (no vegetables due to calories), probiotic waters like Geral Steiner and San Pellegrino. Avoid pasteurized processed American spring waters lacking living microbes.
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Jim references David Sinclair's research claiming complete aging reversal in mice and monkeys, soon in humans.
Respect for Dr. Sinclair, Harvard researcher published extensively on slowing aging. Impressed with his healthy appearance, reflecting outward and inward health via MRIs. Emphasis on external exogenous strategies, not lifestyle for reversing aging. Potential financial conflicts from involvement in supplement companies promoting targets via supplements, unlike lifestyle approaches here. More effective to use endogenous manipulation inside the body rather than exogenous sources. Cred to Sinclair as accomplished researcher.
David Smith asks about recommended fasting probiotics containing resistant starch or inulin. ChatGPT says skip if containing those, as autophagy continues with less than 1g carbs.
Inulin is a prebiotic feeding beneficial microbes as stored energy source like concentrated sugar for microbes, but caloric. In fasted state, signals body to turn off autophagy, the disease-reversing process. Not a fan of inulin even in fed state; avoids it in yogurts and L. reuteri/L. gasseri, preferring microbes use lactose over non-fermented inulin, concerned about cellular impacts. Agree: skip inulin or other prebiotics. Seek probiotics without them. Emerging probiotic-prebiotic combos warrant caution—prefer plain probiotics.
Capsules often unhelpful or harmful; many are delayed release (DR) to reach further in tract, but body's defense system lets favorable microbes pass without capsules. Consider capsule material. Respect to David.
David asks if cartilage can regenerate naturally without stem cells and bioactive materials.
Qualify without exogenous stem cells (harvested from body, manipulated outside, reinjected invasively). Prefer endogenous stem cells over exo, as artificial movement bypasses body's ingenious system for production and targeted delivery. Processing compromises control of hypertrophy/growth, like turning whole food processed. Avoid exogenous stem cells; use lifestyle optimization to upregulate endogenous stem cells.
Future improvements in endogenous production/restoration of collagen possible, especially for diseased/injured states. Severed tendon unlikely to regenerate without divine intervention, but torn, strained, diseased tissues can improve via endogenous stem cells, growth factors, adiponectin, reducing inflammatory molecules and toxicity like eliminating visceral fat. Expect improvements in quality and quantity of ligaments, tendons, collagen.
MD researcher specializing in eliminating deadly visceral fat around abdomen/heart (heart attack/stroke risk) and inflammatory fat in muscles. Works with US senators, congressmen, governors, senior executives, ambassadors. Example: senior corporate member transformed in 3 months; senior executive in 11 months. Disease loss, not weight loss. Visit dranomalo.com or link for practice.
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