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Ben Greenfield Injects This on Every Flight. Here Is His Complete Travel Protocol.

Mikhaila PetersonJuly 2, 20266m
In a Nutshell

Ben Greenfield uses low-dose retatrutide (0.25 mg) on travel days to control appetite and KPV injections daily to eliminate gut issues. He stacks morning tesamorelin with evening ipamorelin (5 days on, 2 off) for growth hormone, visceral fat reduction, and recovery, and applies a 1,300 mg NAD transdermal patch to combat travel fatigue. He warns that easy online peptide access is ending due to regulatory crackdowns, pushing users toward compounding pharmacies.

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Ben Greenfield experiences significant digestive disruption when traveling, often developing loose stools from minor dietary deviations that do not occur at home. He now travels with KPV peptide and injects it every morning, which eliminates nearly all gut issues during travel. The guest confirmed loving KPV as well, noting it was recommended by Gabriel Lyon and produces a noticeable physiological calming effect. Greenfield stated he continues only interventions he can clearly feel working.

Larazotide was mentioned as an option, though it is primarily for general gut inflammation rather than leaky gut or barrier repair. Oral BPC-157 was suggested as another approach for gut inflammation. Greenfield acknowledged the lack of long-term human clinical research on peptides but emphasized they are short chains of amino acids that act with precision on targeted systems. He noted that reported side effects typically stem from low-quality Chinese imports purchased from non-CGMP "bargain bin" websites rather than the peptides themselves.

The industry is undergoing significant regulatory pressure, with cease-and-desist letters being issued to many fly-by-night peptide websites. One site the guest previously used has shut down. Peptide Sciences was identified as one of the larger operations that has closed. Greenfield predicts that familiar peptides such as the GLPs and SS-31 (a mitochondrial brain-support peptide) will transition into pharmaceutical channels, while others will become available through 503A compounding pharmacies operating under good manufacturing practices. The era of directly purchasing peptides online via influencer discount codes is likely ending.

Greenfield recommended three peptides for further investigation, prefacing with the disclaimer that he is not a doctor and this is not medical advice.

Retatrutide, a triple agonist acting on three hunger pathways, is used specifically on airplane travel days at a low dose of 0.25 mg to suppress appetite when access to quality food is limited. This prevents both excessive caloric intake and unwanted muscle loss. Greenfield avoids higher or more frequent dosing (such as 2.5 mg or three times weekly) because he is a hard gainer and does not want to lose muscle mass. Studies showing muscle effects typically use doses of 2.5 mg or higher.

For growth hormone support, visceral fat reduction, muscle maintenance, and recovery, Greenfield recommends stacking tesamorelin in the morning with ipamorelin in the evening. Tesamorelin promotes growth hormone release while specifically decreasing visceral fat accumulation around organs. The protocol follows a 12-week cycle of 5 days on and 2 days off. Ipamorelin additionally aids sleep but requires low blood glucose and insulin levels, necessitating an early dinner (e.g., 6:00 p.m.) with injection at 7:30–8:30 p.m.

For individuals averse to needles, microneedle patches can deliver peptides within 8–10 minutes. Longer-term transdermal patches are available for compounds such as NAD. On travel days, Greenfield injects retatrutide and applies an NAD patch that slowly delivers 1,300 mg of NAD transdermally. This combination mitigates travel fatigue, sleep deprivation, and general malaise associated with flying.

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