Gum Disease Is Not a Dental Problem. It Is a Metabolic One.
In a Nutshell
Porphyromonas gingivalis is a keystone oral pathogen that drives systemic metabolic disease by destroying beneficial brown adipose tissue, disrupting gut barrier integrity, and triggering insulin resistance and visceral fat inflammation. Fermented foods applied directly via dental floss eliminated chronic dental pain in two days by restoring microbial balance, while sprint intervals, dry-fire saunas, and spring water outperform conventional fitness and hygiene practices for reducing disease-causing fat depots. Early visible signs such as spider veins and penile skin discoloration signal metabolic breakdown long before erectile dysfunction or heart attack.
These notes were generated by AI and may contain inaccuracies.
PG is a gram-negative anaerobic bacterium that lives principally in the subgingival biofilm. This microbe is considered a keystone periodontal pathogen, meaning even at relatively low prevalence abundance it can disrupt the normal oral microbiome and manipulate the immune response. PG literally eats gums, causing teeth to appear long with receding gum lines. The bacterium lives around the gums and consumes flesh particularly in and around teeth and the gum line.
Biofilms are collections of mucinous biologic tissue that start forming and collecting within the mouth on the tongue, and biofilms can even get into the gastrointestinal tract. Biofilms live and line the inside of the gastrointestinal tract. Biofilms are a place where both bad and good players can hang out. The goal is to get as many beneficial microbes inside and a variety of them, while keeping as few bad players as possible.
n A study demonstrated that vaccines in the future may be administered through dental floss because dental floss proved more effective for administering vaccines than shots and oral polio vaccine when measuring IgG and IgM antibody response. The mouth is a very rich immunogenic area. Eating poor quality food feeds the bad pathogens in the mouth, denaturing, attenuating, and harming the immune system present there.
PG utilizes potent proteolytic enzymes called gingipains and lipopolysaccharides. These fragments of pathogenic microbes, even when the microbes die, can still cause harm. The lipopolysaccharides are pieces of the microbes that remain problematic even after death.
There is a causal relationship between PG and periodontitis, causing actual disease in gum tissues. There is an increasing association between PG and atherosclerosis, cardiovascular disease, heart attacks, strokes, rheumatoid arthritis, autoimmune disorders, Alzheimer's, dementia, diabetes, metabolic dysfunction, liver disease, cancers, and adverse events during pregnancy. PG is also connected to systemic inflammation throughout the body originating from the mouth.
For most of these systemic diseases, the association is mechanistic evidence but definitive proof of human causation has not been established because causation studies would require inducing harm in humans, which is problematic for research institutional review boards.
If pregnant or of childbearing age, PG is associated with pre-term birth, low birth weight, fetal growth restriction, preeclampsia, and other adverse pregnancy conditions. There is also a connection to psychiatric conditions including depression, mood disorders, and anxiety connected to PG and systemic inflammation.
After reading the study about dental floss being superior to intramuscular injections for vaccines, the speaker used dental floss to administer fermented foods and brine to his teeth. He had experienced constant dental pain every single day for three years and could not chew on his right side. After two days of using fermented foods with dental floss, the dental pain was gone and has never returned.
The study examined different areas of fat in the body and the impact of PG on those areas. PG orally influences the oral-gut microbiome leading to dysbiosis, which decreases beneficial microbes in the gut. It impairs the intestinal barrier by disrupting epithelial cells that line the gut, leading to leaky gut where substances that should not enter the bloodstream leak through.
This leads to more gingipains and proteolytic enzymes getting into the body, causing systemic innate immune activation. Problems from overactivation of the immune system can lead to insulin resistance, adipose tissue inflammation, and dysfunctionality of fat depots including visceral fat, ectopic fat, fat around the heart, and fat within muscle.
PG altered the endocrine and metabolic behavior of brown adipose tissue, which is rich in mitochondria and produces ATP. This beneficial fat generates heat through thermogenesis. PG attacked the good fat more than virulent disease fat like visceral fat and deep subcutaneous fat, showing a predilection for affecting beneficial fat disproportionately.
Subcutaneous fat is made up of two compartments: deep and superficial. The study only measured markers including adiponectin at the 18-hour point. This was a rodent study, not human research. PG lowered adiponectin by 65%, which chiefly comes from superficial subcutaneous fat.
PG affected genes, downregulating them. Of the genes that went up, 42% were associated with metabolic processes. Among the genes that went down, approximately 79% were metabolic process genes. The microbe had tremendous effects on metabolism both from an endocrine perspective and genetic expression.
Brown fat is not simply a heat-generating furnace that can be increased by cold plunging and cold showers. It is also an endocrine organ that releases signaling molecules called batokines. These batokines declined as a result of PG prevalence, meaning loss of endocrine functionality occurs with this type of infection.
Fermented foods are better described as living food. They are alive and bring living microbes inside the body that can colonize and potentially live in the body for the rest of life through engraftment. Fermented foods have a way higher asymmetry of good microbes rather than bad. Living microbes produce metabolites that create signals leading to physiological responses like the body making GLP-1. Natural approaches have no side effects.
Practice good dental care including brushing, preferably with natural boar bristle brushes. Occasionally use an electronic toothbrush but not too much due to vibration. Use a water pick, dental picks, and other pick tools. A video titled "How to Bulletproof Your Mouth, Teeth, Gums, and Lips" provides additional suggestions.
Zone one cardio is great, particularly walking. Zone two can also be achieved with a brisk walk. Avoid the upper end of zone two where light jogging occurs. Instead, do interval training with walking combined with intense efforts like sprinting, sprint cycling, sprint swimming, or push-ups to exhaustion. This approach works best to eliminate inflammatory fat around the heart.
Jogging produces more degenerative joint disease than sprinting. Start slow and work up to sprinting. Get cleared by a doctor before beginning sprinting due to exertion requirements. Strain, tear, or injury risk exists if not appropriately prepared, especially with existing visceral fat.
Nature had humans sprinting either after prey to hunt or to escape threats. Mix up sprint frequency rather than following a rigid program. One day do one sprint, next day do ten sprints, next day do none, following day do five. Nature likes variety and introduces challenges unpredictably. On average, approximately six sprints every other day throughout the year is a reasonable target, but mix it up rather than averaging consistently.
Promote variety and mixing things up. Thoughts on gyms getting rid of saunas that heat up to 180 degrees or more and replacing them with infrared radiationless saunas. This approach is considered crazy and likely driven by cost-saving measures since infrared saunas are cheaper. Stick with dry fire saunas like those used by the YMCA and YWCA. Most studies, including the best studies, have been done looking at dry fire saunas - the kind with heat generators using rocks. Stay away from infrared kinds because they represent an artificial heat source. The infrared coming out of an infrared sauna is very different from the infrared that comes from the sun. Get infrared from the sun, but don't get it anywhere else. Stick with nature. The heat is what matters. The only impact otherwise might be some Wi-Fi, so get a little generator down there. Scientifically there's no difference when a rock heats up - it's not going to be any different than if it's heated up from wood burning in a fire, a wigwam, or a volcano, but infrared is very different.
There are studies that have associated the consumption of extra virgin olive oil (EVO) with a decreased amount of visceral fat. There are also studies and anecdotal experience with saturated fat from ghee showing similar effects. Olive oil is probably not as good as getting animal good quality grass-fed ghee, which is preferred over olive oil. However, some olive oil has been associated with reduction of visceral fat in studies.
The fitness industry is not tracking things except for people losing all of their superficial, beneficial subcutaneous fat. The fitness industry unfortunately promotes the loss of fat, especially on the outside of the body. Everybody is trying to get a six-pack, but this causes loss of that superficial subcutaneous fat. There is no science showing that a visible six-pack makes you more healthy. When this happens, people unfortunately still retain all of this deadly inflammatory fat deep inside. The fitness industry is not tracking what really matters - what's aligned with true health, optimizing health, and elimination of disease. The fitness industry promotes a bodybuilding physique with low subcutaneous fat, particularly the superficial subcutaneous fat, and complete ignorance. They attack fat like crazy, but what about the disease fat that's filling your muscle? And the fat around your heart? A podcast with Dr. Mike Ezraal, PhD is coming out soon. He got a full body scan and the fat inside of him was examined. If you're in the bodybuilding industry or fitness industry, get an MRI to see what's going on. Start tracking what really matters. It's not cholesterol, and it's not trying to make your fat disappear so you can see a six-pack.
Use spring water for the water pick. Absolutely use spring water - there's no chlorinated water going inside the mouth or going in the body. Don't take showers with chlorinated water either. Get non-chlorinated water for years by going to get spring water in five gallon jugs and glass jars. Used to do cowboy shower pour-overs. Now using an Aphora non-chlorinated cold plunge, which serves as a shower. Chlorine in the mouth is connected with carcinogenesis and is associated with increasing and causing cancer, probably mediated through disrupting the microbiome. Do not get chlorine in your mouth.
Spider veins are one of the earliest signs that someone's metabolism is breaking down. Looking at spider veins and telangiectasias - these small little purplish veins that start forming around the ankles, medial thighs of the thighs in women, and on the skin of the penis in guys. The skin of the penis turns into what is described as a purple kabasa. Nice pink healthy skin at ages 15-18 years old changes to look like kabasa with all these veins - gross and diseased, with poor blood flow. This is one of the earliest signs of metabolic dysfunction that manifests in the skin as a change in blood vessels for the worst. It precedes way in advance of erectile dysfunction. The earliest sign of a heart attack is not lack of erection - long before that, purple gross injectas appear on ankles, thighs, and the skin of the foreskin and skin of the penis.
Ocean water is sipped because it's one of the most microbiotic areas of water that can be exposed to. Better areas should be selected for harvesting - not around sewer pipe treatment areas like coming out of Los Angeles, but from places like Naples. Frequent regular surfers are never really seen as fat, and they're all really healthy looking. Surfer dudes are loved by women, and surfer babes are high. This isn't because the surfboard is magically doing that - it's the microbes in the water. Client patients are instructed to drink ocean water.
When movement stops for most of the day, probably not a lot of great things happen. Some movement is predominantly needed, including some high intensity briefly, but workouts don't need to be done nearly as much as commonly recommended. Workout routine involves five minutes a day or about 15 minutes every three days. At 63 years old, no steroids, stem cells, peptides, hormones, or performance-enhancing drugs have ever been taken. This approach has been maintained for the past 15 years. Old de look great - old humans should look great. The difference is that animals in the wild eat healthy, while humans eat terrible unless they know how to eat.
After losing 115 pounds but unable to lose the last 60 pounds, get an MRI to see what's going on. The biggest problem is metabolic dysfunction from all that visceral fat causing insulin resistance. The ultimate start program can help get an MRI and take it to new levels.
In certain areas society is getting healthier, but unfortunately the amount of chronic disease is accelerating. More prevalence of chronic disease has never been seen in a lifetime than currently exists. Unfortunately, getting worse more than getting better.
Stairmaster is a substitute for sprinting, though not necessarily a good substitute. Better alternatives would be sprint swimming if a non-chlorinated pool can be found. Do the best possible. Sprint cycling, stair master, stair climber - something brief and intense that can be done for a while that challenges and gets short of breath. The end state should be being short of breath. Gym bros and gym babes wanting six-packs grunt for a little bit, but should be gasping for air like after doing a sprint. Work toward this in workouts.
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