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How to Hit ‘Reset’ on a Broken Microbiome

Nick NorwitzFebruary 13, 202616m
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Early humans lived in dirt around animals in real sunlight with real darkness. Food was unprocessed, unsterile, and full of microbes that co-evolved with us. Guts and environments were in harmony. Today, microbes are under attack by sugary breakfast cereals, stressful jobs, pesticides, antibiotics, and long ingredient lists. We live in a world our biology doesn't recognize, reflected in health.

Speaker's personal story: As a newborn, had 106°F fever; doctors gave strong antibiotics, scarring microbiome for life, increasing inflammatory bowel disease risk by 500%, which developed.

Big question: If gut ecosystem is broken, can you hit reset?

Diversity breeds resilience. Fiber elimination diets induce remission in 60-85% of inflammatory bowel disease cases. Defines fitness as tolerance to challenge. Interventions can impair metabolic health through microbiome disruption.

Four phases: 1. Elimination, 2. Early Repopulation (or repopulation), 3. Advanced Repopulation and Challenge, 4. Maintenance. Covers diet specifics, food selection, sequencing, beyond diet.

Wipe slate clean like shaking an etch sketch, not making microbiome sterile (impossible, avoid antibiotics). Use elimination diet to starve bad bugs/pathogens. Most effective: animal-based carnivore-style for ~8 weeks. Removes plant material that feeds gut microbiota (good and bad), starves problematic pathogenic species and sugar feeders.

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