How to Use D3 and K2 to Heal Arteries
In a Nutshell
Take vitamin D3 only as needed to reach blood levels of 50-90 ng/mL, typically 2,000-5,000 IU daily, and never exceed 90 ng/mL. Take at least 400 mcg of K2 daily as separate supplements rather than combination pills, since K2 primarily works by improving insulin resistance rather than removing calcium from arteries. Standard combination pills force excessive D3 dosing to reach effective K2 amounts and can cause kidney damage even with magnesium supplementation.
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Vitamin D3 and K2 are two of the most important supplements available. There is clear evidence that they help arteries by preventing dangerous arterial plaque buildup. Most people take them incorrectly, which can result in healthier arteries versus wasted money or actual body damage. Some people have died from taking these supplements incorrectly in wrong doses.
The most purchased D3 and K2 combination pill provides 90 micrograms of K2 and 5,000 international units of D3. To reach a K2 dose that has been studied and shown to work, four of those pills would be needed. This results in 20,000 international units of D3 daily, which is not recommended. Taking magnesium with high D3 doses does not prevent problems, as multiple patients have experienced kidney function issues and kidney damage despite magnesium supplementation. A doctor reported a patient who died from taking higher D3 doses.
A study following men over time found that those with vitamin D3 levels below 30 had higher heart attack risk than those at 30 or above. Men with levels below 15 had 2.5 times higher risk. Men with levels between 22 to 30 still had about 60% more risk for heart attack, despite most labs considering this range acceptable.
The VITAL trial with 25,871 people tested 2,000 international units of D3 daily versus placebo over a median of 5.3 years. The D3 group showed no significant reduction in cardiovascular events. This result occurred because most participants were not deficient initially, and a fixed dose was given without measuring actual D3 levels achieved.
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